Protexin Denamarin tabs for Medium dogs 225MG High level nutritional support for the liver. Denamarin provides multi-faceted high level nutritional support for the liver due to its synergistic combination of S-adenosylmethionine (SAMe) and silybin. Protects SAM-e from degradation to support the liver's natural function. Denamarin contains: A stabilised form of the S, S-SAMe isomer, the predominant form synthesised in cells and the isomer which is biologically active. Silybin complexed with phosphatidylcholine, which has been shown to be more bioavailable than silymarin alone. The enteric coating of Denamarin protects the SAMe from degradation. Denamarin is also blister packed to prevent oxidation of the SAMe to the non-biologically active R, S-SAMe isomer. The product is manufactured to high quality standards to ensure the label claim is met. Composition: (Milk thistle extract/ phosphatidylcholine complex), mannitol. Nutritional Additives (perkg): Methione (As S- Silybinphytosome Adenosylmethione), Same: 425mg, Silybin: 35mg. Weight Tablets < 5kg 1 5 - 15kg 1 15 - 30kg 1 30 - 55kg 2 >55kg 3 Tablets should be given on an empty stomach at least one hour before a meal for optimum absorption (an overnight fast is preferred). The number of tablets administered may gradually be reduced, or increased, at any time at the recommendation of your veterinary surgeon. Animals with diagnosis of liver disease or insufficiency from their vet, however this is a supplement, not a treatment or medication for the above. .